-The aim of the study For different nanoparticles (platinum, gold, silver, iron), different nano sizes (5, 10, 30, 50, 70 nm), different concentrations (4, 6, 12, 18, 24, 30 mg NP/g), different nano shapes (cubic, cylindrical, spherical), at different PTV depths (1 cm and 5 cm from the surface) and at different energies (60, 80, 100, 150 and 250 kV - 2, 4, 6 MV X-ray) to calculate the dose enhancement factor (DEF).
DEF: (Dose with NPs on Nano Lattice method) / (Dose withOUT NPs on Nano Lattice method)
-I want to measure the point dose at 6 points on the edges of the PTV (5 mm away from the PTV) to see if the nanoparticles contribute to the dose at 5 mm away.( I wrote 1, 2 and 3 on the picture. but there will be 6.)
- There are many different simulation calculations, but it may be enough to write 1 (maybe 2) codes. Because I think it would be enough to change only particles, energies, concentrations on the code, but you know better.
-SSD for kV energies: 20 cm, SSD for MV energies: 100 cm.
-PTV dimensions: 1 cm x 1 cm x 1 cm x 1 cm
-Radiation area 5x5 cm2
-Large phantom sizes can be 10x10 cm2.
-The structure of the soft tissue should be as specified in ICRU: 10.1% hydrogen, 11.1% carbon, 2.6% nitrogen, 76.2% oxygen.
-For example (for one simulation): The nanoparticle is gold, shape cylindrical, size 50 nm, concentration 6 mg Au/g, PTV depth 1 cm, SSD:20 cm, energy:150 kV.
-To make sure that the mcnp on my computer will work correctly, I want to do one sample simulation together on our computers. I want to do the rest of the simulations on my computer.
- In an article electron emission properties (secondary electron production, electron ejection effect, I don't quite understand) were analysed. can we look at this? I have attached the sample graph.
If there is anything unclear, please ask. we can discuss it. Thank you so much!
